Learn About Normal Pressure Hydrocephalus
Hydrocephalus is a buildup of spinal fluid inside the fluid chambers of the brain. Hydrocephalus means "water on the brain."
Normal pressure hydrocephalus (NPH) is a rise in the amount of cerebrospinal fluid (CSF) in the brain that affects brain function. However, the pressure of the fluid is usually normal.
Hydrocephalus - occult; Hydrocephalus - idiopathic; Hydrocephalus - adult; Hydrocephalus - communicating; Dementia - hydrocephalus; NPH
There is no known cause for NPH. But the chance of developing NPH is high in someone who previously had any of the following:
- Bleeding from a blood vessel or aneurysm in the brain (subarachnoid hemorrhage)
- Certain head injuries
- Meningitis or similar infections
- Surgery on the brain (craniotomy)
As CSF builds up in the brain, the fluid-filled chambers (ventricles) of the brain swell. This causes pressure on brain tissue. This can damage or destroy parts of the brain.
Symptoms of NPH often begin slowly. There are three main symptoms of NPH:
- Changes in the way a person walks: difficulty when beginning to walk (gait apraxia), feeling as if your feet are stuck to the ground (magnetic gait)
- Slowing of mental function: forgetfulness, difficulty paying attention, apathy or no mood
- Problems controlling urine (urinary incontinence), and sometimes controlling stools (bowel incontinence)
Diagnosis of NPH can be made if any of the above symptoms occur and NPH is suspected and testing is done.
Treatment for NPH usually requires surgery to place a tube called a shunt that routes the excess CSF out of the brain ventricles and into the abdomen. This is called a ventriculoperitoneal shunt.
Lifespan Physician Group Inc
Petra Klinge is a Neurosurgery provider in North Providence, Rhode Island. Dr. Klinge and is rated as an Elite provider by MediFind in the treatment of Normal Pressure Hydrocephalus. Her top areas of expertise are Tethered Cord Syndrome, Hydrocephalus, Normal Pressure Hydrocephalus, Posterior Fossa Decompression, and Laminectomy.
Yale University
Charles Matouk is a Neurosurgery specialist and an Interventional Radiologist in New Haven, Connecticut. Dr. Matouk and is rated as an Elite provider by MediFind in the treatment of Normal Pressure Hydrocephalus. His top areas of expertise are Stroke, Subarachnoid Hemorrhage, Hydrocephalus, Thrombectomy, and Stent Placement.
Hilkka Soininen practices in Kuopio, Finland. Soininen and is rated as an Elite expert by MediFind in the treatment of Normal Pressure Hydrocephalus. Their top areas of expertise are Dementia, Alzheimer's Disease, Normal Pressure Hydrocephalus, Hormone Replacement Therapy (HRT), and Oophorectomy.
Without treatment, symptoms often get worse and could lead to death.
Surgery improves symptoms in some people. Those with mild symptoms have the best outcome. Walking is the symptom most likely to improve.
Problems that may result from NPH or its treatment include:
- Complications of surgery (infection, bleeding, shunt that does not work well)
- Loss of brain function (dementia) that becomes worse over time
- Injury from falls
- Shortened life span
Contact your provider if:
- You or a loved one is having increasing problems with memory, walking, or urine incontinence.
- A person with NPH worsens to the point where you are unable to care for the person yourself.
Go to the emergency room or call 911 or the local emergency number if a sudden change in mental status occurs. This may mean that another disorder has developed.
Summary: Prospective, multi-center, randomized, controlled trial of the eShunt System in the treatment of patients with normal pressure hydrocephalus.
Summary: The aim of this single-center, two-arm, open-labeled, randomized controlled clinical study is to compare two surgical interventions, endoscopic third ventriculostomy and ventriculoperitoneal shunt, in treating idiopathic normal pressure hydrocephalus in terms of clinical improvement.
Published Date: March 31, 2024
Published By: Joseph V. Campellone, MD, Department of Neurology, Cooper Medical School at Rowan University, Camden, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Frim DM, Vivas-Buitrago T, Rigamonti D, Lacy M. Surgical management of hydrocephalus in the adult. In: Quiñones-Hinojosa A, ed. Schmidek and Sweet: Operative Neurosurgical Techniques. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 81.
Rosenberg GA. Brain edema and disorders of cerebrospinal fluid circulation. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier; 2022:chap 88.
Sivakumar W, Drake JM, Riva-Cambrin J. The role of endoscopic third ventriculostomy: a critical review. In: Winn HR, ed. Youmans and Winn Neurological Surgery. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 45.